郭晶

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  姓      名:郭晶
  学      历:博士
  职      称:讲师
  院系部门:动物科学系
  专      业:动物医学
  联系方式:18263580755    E-mail:guojing2360846@163.com

个人简介

郭晶,女,博士,1984年生,山东临清人。2008年本科毕业于聊城大学农学院。2008-2014年在中国农业科学院哈尔滨兽医研究所国家禽流感参考实验室攻读硕士和博士学位。2014年博士毕业后在中国农业科学院兰州兽医研究所工作,2016年调至聊城大学农学院。主要研究方向为:流感病毒的致病和传播机制;病毒与宿主互作机制等。截止目前发表研究论文14篇,代表性研究成果以第一作者发表在国际顶级期刊Science和病原学权威期刊PLoS pathogens上。曾获中国农业科学院优秀博士论文奖、中国农业科学院优秀博士毕业生、2013年度国家奖学金等奖励。


教学工作

承担本科生:《畜牧微生物学》、《兽医生物制品学》、《现代仪器分析》、《生物化学实验》等课程的教学工作。


研究方向

主要研究方向动物病毒学。


科研项目

  1. 国家自然科学基金面上项目、81571998,树鼩H5亚型高致病性禽流感病毒感染模型创建及应用、105万、2016/01-2019/12、在研、参加
  2. 聊城大学博士基金、H9N2亚型禽流感病毒树鼩适应性研究及分子机制、8万、2017/01-2019/12、在研、主持

代表性成果

  1. Xuyong Li#, Jianzhong Shi#, Jing Guo#, Guohua Deng, Qianyi Zhang, Jinliang Wang, Xijun He, Kaicheng Wang, Jiming Chen, Yuanyuan Li, Jun Fan, Huihui Kong, Chunyang Gu, Yuntao Guan, Yasuo Suzuki, Yoshihiro Kawaoka, Liling Liu, Yongping Jiang, Guobin Tian, Yambing Li, Zhigao Bu, Hualan Chen*, Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses, PLoS pathogens, 2014, 10:e1004508
  2. Qianyi Zhang#, Jianzhong Shi#, Guohua Deng#, Jing Guo#, Xianying Zeng#, Xijun He, Huihui Kong, Chunyang Gu, Xuyong Li, Jinxiong Liu, Guojun Wang,Yan Chen, Liling Liu, Libin Liang, Yuanyuan Li, Jun Fan, Jinliang Wang,Wenhui Li, Lizheng Guan, Qimeng Li, Huanliang Yang, Pucheng Chen, Li Jiang, Yuntao Guan, Xiaoguang Xin, Yongping Jiang, Guobin Tian, Xiurong Wang, Chuanling Qiao, Chengjun Li, Zhigao Bu, Hualan Chen*, H7N9 influenza viruses are transmissible in ferrets by respiratory droplet, Science, 2013, 341:410-414
  3. Xuyong Li#, Jiayun Yang#, , Bin Liu, Yane Jia, Jing Guo, Xue Gao, Shaoting Weng,Maijuan Yang, Liang Wang, Lin-Fa Wang, Jie Cui, Hualan Chen*, Qiyun Zhu*. 2016. Co-circulation of H5N6, H3N2, H3N8, and Emergence of Novel Reassortant H3N6 in a Local Community in Hunan Province in China. Scientific reports 6:25549.
  4. Xuyong Li#, Yuguang Fu, Jiayun Yang, Jing Guo, Jijun He, Jianhong Guo, ShaotingWeng, Yane Jia, Bin Liu, Xiaoyang Li, Qiyun Zhu*, Hualan Chen*. Genetic and biological characterization of two novel reassortant H5N6 swine influenza viruses in mice and chickens. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2015, 36:462-466.
  5. Hong Zhang#, Xuyong Li#, Jing Guo, Li Li, Chong Chang,Yuanyuan Li, Chao Bian, Ke Xu, Hualan Chen*, Bing Sun*. The PB2 E627K mutation contributes to the high polymerase activity and enhanced replication of H7N9 influenza virus. The Journal of general virology, 2014, 95:779-786.
  6. Jianzhong Shi#, Guohua Guo#, Peihong Liu, Jinping Zhou, Lizheng Guan, Wenhui Li, Xuyong Li, Jing Guo, GuoJun Wang, Jun Fan, Jinliang Wang, Yuanyuan Li, Yongping Jiang, Liling Liu, Guobin Tian, Chengjun Li*, Hualan Chen*. Isolation and characterization of H7N9 viruses from live poultry markets — Implication of the source of current H7N9 infection in humans, Chinese Science Bulletin, 2013, 58:1857-1863
  7. Jianzhong Shi#, Zhiyuan Wen, Jing Guo, Ying Zhang, Guohua Deng, Yuelong Shu, Dayan Wang, Yongping Jiang, Yoshihiro Kawaok, Zhigao Bu, Hualan Chen*. Protective efficacy of an H1N1 cold-adapted live vaccine against the 2009 pandemic H1N1, seasonal H1N1, and H5N1 influenza viruses in mice. Antiviral research, 2012, 93:346-353.
  8. Huanliang Yang#, Yan Chen, Jianzhong Shi, Jing Guo, Xiaoguang Xin, Jian Zhang, Dayan Wang, Yuelong Shu, Chuanling Qiao *, Hualan Chen. Reassortant H1N1 influenza virus vaccines protect pigs against pandemic H1N1 influenza virus and H1N2 swine influenza virus challenge. Veterinary microbiology, 2011. 152:229-234.
  9. 郭晶,李旭勇钟功勋施建忠李雁冰陈化兰*,两株H5N1高致病性禽流感病毒对小鼠的致病力研究,中国预防兽医学报,2014,36 (11):834-837
  10. 陈佳宁,郭晶,李旭勇,陈化兰*,禽流感病毒NS2蛋白的原核表达及多克隆抗体的制备,中国预防兽医学报,2010,34 (6):489-491
  11. 王金良,李旭勇,范俊,郭晶,邓国华,施建忠,陈化兰*,H9N2亚型禽流感病毒的序列分析及对哺乳动物致病力研究,中国预防兽医学报,2013,35 (8):663-665
  12. 范俊,李旭勇,王金良,郭晶,邓国华,施建忠,陈化兰*,7.2分支H5N1亚型禽流感病毒反向遗传疫苗候选株的构建,中国预防兽医学报,2013,35 (9):764-766
  13. 李旭勇,郭晶,施建忠,李雁冰,陈化兰*,H5N1亚型禽流感病毒低剂量感染小鼠发病模型的建立,中国预防兽医学报,2011,33(7):503-506
  14. 杨佳运,李旭勇,贾艳娥,郭晶,翁少亭,高雪,朱启运*,H4和H6亚型禽流感病毒血凝素蛋白特异性单因子血清的制备,中国兽医科学,2015,45(10):1058-1063
  15. 李媛媛,郭晶,李旭勇,王金良,范俊,梁立滨,邓国华,施建忠,陈化兰*,H7N9亚型禽流感病毒反向遗传操作系统的建立及其疫苗候选株的构建. 中国预防兽医学报,2014,36(5):407-409